Danaher Corp. will acquire Irvine-based medical device maker Masimo Corp. for nearly $10 billion, a deal that further underscores Irvine’s growing role as a hub for medical technology and health care innovation.

Masimo develops patient-monitoring technologies such as pulse oximeters, noninvasive sensors and related software used in hospitals and acute care settings worldwide. Danaher, a Washington, D.C.-based science and technology company, operates across biotechnology, life sciences and diagnostics.

Masimo will operate as a standalone company within Danaher’s diagnostics segment. The transaction is expected to close in the second half of 2026, pending approvals.